地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话:18327026838
传真:18771149750
邮箱:sales@amyjet.com

QED Bioscience致力于为生物医药行业提供各类高品质抗体。
QED Bioscience has been designing and manufacturing antibodies for over 20 years, and throughout our history, our goals have remained unchanged: provide the best antibody products and services on the market and support our clients with the expertise and assistance they should expect from a full-spectrum antibody company like QED.
QED Bioscience develops novel monoclonal and polyclonal antibody products for our academic, biotechnology, diagnostic and pharmaceutical research clients. We develop these antibodies using the client’s small molecule, protein, or peptide targets, or by utilizing the target cDNA. We are a full-service corporation, and offer additional immunochemistry services such as purification and conjugation so that we can provide our clients with an antibody product that will work specifically within their system. We also develop monoclonal antibodies with pharmacological activity for enzyme neutralization and inhibition of receptor-ligand interactions, and anti-idiotypic antibodies.
QED Bioscience的主要产品包括:
Agriculture and Food Science Antibodies
Anti-Immunoglobulin Antibodies
Apoptosis Antibodies
Autophagy Antibodies
BioWarfare Antibodies
Cancer Research Antibodies
Cell Adhesion Molecule Antibodies
Coagulation Factor Antibodies
DNA/RNA/Oxidative Stress Antibodies
Drug Antibodies
Enzymes and Enzyme Inhibitor Antibodies
Epitope Tag Antibodies
Growth Factors/Cytokines/Receptor Antibodies
Heat Shock and Stress Protein Antibodies
Hormones and Serum Protein Antibodies
Infectious Disease Antibodies
Ion Channel Antibodies
Matrix Protein/MMP Antibodies
Neuroscience and Signal Transduction Antibodies
Phospho-specific Antibodies
Protein Transcription Antibodies
Reproductive Biology Antibodies
Secondary Antibodies
<更多详情请联系
艾美捷科技有限公司
全国服务热线:400-6800-868
邮箱:sales@amyjet.com
网站:www.amyjet.com
<艾美捷科技代理Essange Reagents品牌全系列产品
Essange Reagents的核心使命是开发与分销精密工程化试剂,专注于血型鉴定试剂及特定血浆蛋白产品的研发生产。这些试剂严格遵循ISO13485标准精心制备,适用于体外诊断(IVD)和科研专用(RUO),为研究人员与医疗从业者提供可靠、可重复的结果支撑,助力其精准达成科研目标。Essange Reagents的IgG亚类试剂及多数CD单克隆抗体(专用于诊断领域)均经过全面技术文献验证。
▎Essange Reagents产品线
● 血型血清学:Cellbind微柱凝集卡、抗血清、试剂红细胞、Cellbind卡专用Magister C24全自动系统;
● 免疫试剂:IgG亚类试剂、单核细胞活化检测试剂、ELISA产品以及其他生物制品。

▎Essange Reagents产品列表
| 品名 | 货号 | Product group | 规格 | Techique |
| PeliCluster Anti-Lactoferrin | M9160BBC | Cytokines Immune reagents | 5 mg | Flowcytometry |
| PeliCluster Anti-CD62P | M9048BBC | Cytokines Immune reagents | 5 mg | Flowcytometry |
| PeliCluster Anti-Granzyme B with azide | M9174ABD | Immune reagents | 10 mg | Flowcytometry |
| PeliCluster Anti-Granzyme B | M9174 | Immune reagents | 5 mg | Flowcytometry |
| Anti-Vedolizumab antibody | M9265 | Biologics | - | ELISA |
| Anti-Tocilizumab antibody | M9264 | Biologics | - | ELISA |
| Anti-Dupilumab antibody | M9263 | Biologics | - | ELISA |
| Anti-Guselkumab antibody | M9262 | Biologics | - | ELISA |
| Anti-Daratumumab antibody | M9261 | Biologics | - | ELISA |
| PeliKine Human IL-6 ELISA Rapid Set A | M2018 | MAT | - | - |
| PeliKine Human IL-6 ELISA Rapid Set B | M2019 | MAT | - | - |
| Cellbind P3-P | K7211 | Blood grouping reagents Column | 3x10 mL | Cellbind |
| PEG 4000 20% | K1159 | Blood grouping reagents Potentiator | 20 mL | PEG-IAT: spin tube |
| PeliLISS | K1110 | Blood grouping reagents Potentiator | 10 mL | LISS-IAT: spin tube |
| BSA 22% (bovine serum albumin) | K1106 | Blood grouping reagents Potentiator | 10 mL | BSA-IAT: spin tube |
| PeliClass human IgG subclass Plus control 2 | M1898 | IgG subclasses IMMAGE | - | Nephelometry |
| PeliClass human IgG subclass Plus control 1 | M1897 | IgG subclasses IMMAGE | - | Nephelometry |
| PeliClass human IgG subclass Plus calibrator set | M1896 | IgG subclasses IMMAGE | - | Nephelometry |
| PeliClass sheep anti human IgG4 Plus | M1894 | IgG subclasses IMMAGE | - | Nephelometry |
| PeliClass sheep anti human IgG3 Plus | M1893 | IgG subclasses IMMAGE | - | Nephelometry |
| PeliClass sheep anti human IgG2 Plus | M1892 | IgG subclasses IMMAGE | - | Nephelometry |
| PeliClass sheep anti human IgG1 Plus | M1891 | IgG subclasses IMMAGE | - | Nephelometry |
| PeliClass human IgG subclass Plus kit | M1895 | IgG subclasses IMMAGE | - | Nephelometry/turbidimetry |
| Magister Control Software | K7320S2 | Blood grouping reagents Instruments Software | 1 piece | Cellbind |
| Magister Analysis Software | K7320S1 | Blood grouping reagents Instruments Software | 1 piece | Cellbind |
| Magister C24 | K7320 | Blood grouping reagents Instruments | 1 piece | Cellbind |
| HPE buffer | M1940 | Immune reagents | 55 mL | - |
| human IL-6 antibodies for ELISA | M9316 | Cytokines Immune reagents | - | - |
| Streptavidin poly-HRP | M2032 | Immune reagents | 1 mL | - |
| Cellbind Incubator | K7314 | Blood grouping reagents Instruments | - | - |
| Cellbind Centrifuge (12 cards) | K7312 | Blood grouping reagents Instruments | - | - |
| Cellbind Dispenser | K7300 | Blood grouping reagents Instruments | - | - |
| Streptavidin poly-HRP | M2051 | Immune reagents | 0,1 mL | - |
| Erytrocytenserologie | K3010 | Blood grouping reagents Educational services | - | - |
| Immunohaematology | K3010EN | Blood grouping reagents Educational services | - | - |
| PeliControl | K1379 | Blood grouping reagents Control | 2x8 ml | - |
| Cellbind DILUENT | K7180 | Blood grouping reagents Column | 100 mL | Cellbind |
| Cellbind LISS | K7130 | Blood grouping reagents Column | 3x25 mL | Cellbind |
| MASPAT Indicator Red Cells | K1139 | Blood grouping reagents Platelet crossmatch | 10 mL | - |
| Cellbind LISS | K7110 | Blood grouping reagents Column | 100 mL | Cellbind |
| MASPAT kit | K1360 | Blood grouping reagents Platelet crossmatch | 96 tests | - |
| MAT Cell Set HS | M2017 | MAT | - | - |
| PeliStrip elution kit | K1398 | Blood grouping reagents Elution | 15 tests | PEG DAT/IAT; spin tube |
| MAT Cell Set | M2016 | MAT | - | - |
| Makropanel 16 | K1385 | Blood grouping reagents Cells | 16x3 mL | IAT: spin tube |
| Screening panel 123 | K1148 | Blood grouping reagents Cells | 3x10 mL | IAT: spin tube |
| Cellbind ID16 | K7230 | Blood grouping reagents Column | 16x3 mL | Cellbind |
| Cellbind P3 | K7210 | Blood grouping reagents Column | 3x10 mL | Cellbind |
| Cellbind P2 | K7200 | Blood grouping reagents Column | 2x10 mL | Cellbind |
| Cellbind B reagent red cells | K7242 | Blood grouping reagents Column | 10 mL | Cellbind |
| Pelikloon polyspecific anti-human serum | K1193 | Blood grouping reagents Coombs sera | 10 mL | (LISS or albumin)-IAT/DAT; spin tube |
| MabTrack ADA infliximab | M2960 | Biologics | - | ELISA |
| Pelikloon anti-C3d monoclonal | K1377 | Blood grouping reagents Coombs sera | 10 mL | DAT; spin tube |
| MabTrack ADA adalimumab | M2950 | Biologics | - | ELISA |
| Pelikloon enhanced control | K1152 | Blood grouping reagents Control | 10 mL | - |
| MabTrack level infliximab | M2920 | Biologics | - | ELISA |
| MabTrack level adalimumab | M2910 | Biologics | - | ELISA |
| Monospecific anti-human IgG (goat) | K1131 | Blood grouping reagents Coombs sera | 10 mL | (LISS or PEG)-IAT/DAT; spin tube |
| anti-H (lectin) saline method | K1327 | ABO Blood grouping reagents | 3 mL | Saline: spin tube |
| Cellbind A1 reagent red cells | K7240 | Blood grouping reagents Column | 10 mL | Cellbind |
| anti-A1 (lectin) saline method | K1328 | ABO Blood grouping reagents | 5 mL | Saline: spin tube, MTP |
| Pelikloon anti-D mix (IgG/IgM) monoclonal | K1157 | Blood grouping reagents Rhesus | 10 mL | Saline, Spin tube, IAT, MTP, Cellbind |
| Pelikloon control monoclonal | K1156 | Blood grouping reagents Control | 10 mL | - |
| anti-Wra AGT method | K1344 | Blood grouping reagents Rare | 3 mL | IAT: spin tube |
| anti-s AGT method | K1343 | Blood grouping reagents Rare | 3 mL | IAT, spin tube |
| anti-Fyb AGT method | K1337 | Blood grouping reagents Rare | 3 mL | IAT, spin tube |
| Pelikloon anti-k (IgM) monoclonal | K1310 | 2 mL | Saline, spin tube | |
| Anti-Fya (IgG) monoclonal AGT method | K1236 | Blood grouping reagents Rare | 3 mL | IAT, spin tube, Cellbind |
| Pelikloon anti-Leb (IgA) monoclonal | K1317 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Pelikloon anti-K (IgM) monoclonal | K1199 | Blood grouping reagents Rare | 5 mL | Saline, Spin tube, MTP, Cellbind |
| Pelikloon anti-Lea (IgM) monoclonal | K1306 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Pelikloon anti-P1 (IgM) monoclonal | K1305 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Pelikloon anti-D enhanced (IgM) monoclonal | K1151 | Blood grouping reagents Rhesus | 10 mL | Saline, Spin tube, MTP, Cellbind |
| Pelikloon anti-D (IgM) monoclonal | K1255 | Blood grouping reagents Rhesus | 10 mL | Saline, Spin tube, MTP, Cellbind |
| Pelikloon anti-S (IgM) monoclonal | K1304 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Pelikloon anti-N (IgG) monoclonal | K1313 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Pelikloon anti-M (IgG) monoclonal | K1302 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Cellbind Direct Type | K7012 | ABO Column | 48 | Cellbind |
| Pelikloon anti-Jkb (IgM) monoclonal | K1301 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Pelikloon anti-Jka (IgM) monoclonal | K1300 | Blood grouping reagents Rare | 2 mL | Saline, spin tube |
| Pelikloon anti-Cw (IgM) monoclonal | K1201 | Blood grouping reagents Rhesus | 2 mL | Saline, spin tube |
| Cellbind Screen | K7000 | Blood grouping reagents Column | 48 cards | Cellbind |
| Pelikloon anti-e (IgM) monoclonal | K1205 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-E (IgM) monoclonal | K1204 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-c (IgM) monoclonal | K1203 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-C (IgM) monoclonal | K1202 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-e (IgM) monoclonal | K1197 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-c (IgM) monoclonal | K1196 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-C (IgM) monoclonal | K1195 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-E (IgM) monoclonal | K1191 | Blood grouping reagents Rhesus | 5 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-A,B (IgM) monoclonal | K1190 | ABO Blood grouping reagents | 3x10 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-B (IgM) monoclonal | K1189 | ABO Blood grouping reagents | 3x10 mL | Saline, spin tube, MTP, Cellbind |
| Pelikloon anti-A (IgM) monoclonal | K1188 | ABO Blood grouping reagents | 3x10 mL | Saline, spin tube, MTP, Cellbind |

艾美捷科技代理USP标准品。
U.S. Pharmacopeia (USP)是一个独立的科学非营利组织,致力于建立优质标准品供应。
USP 一直致力于确保人们可以信赖的安全、优质药品的强大、持续供应。通过其标准、科学专业知识和能力建设解决方案,USP 能够利用由监管机构、行业领导者和制造商组成的全球网络来实现更具弹性的药品供应链。USP 的产品和解决方案包括 USP 参考样品、复合药典、膳食补充剂验证、教育课程和其他资源。范围涵盖:
<生物制剂
抗生素
碳水化合物
细胞、基因与组织
关键试剂
肝素
微生物学
单克隆抗体
寡核苷酸
肽
蛋白质
原材料
疫苗
生物制剂-培训课程
即将推出
可提取物和浸出物(E&L)
膳食补充剂和草药
氨基酸
植物药-草药
矿物质
其他-膳食补充剂
维生素
膳食补充剂和草药-培训课程
即将推出
辅料
赋形剂
黏合剂与填充剂
缓冲剂与pH调节剂
螯合剂
包衣材料
稀释剂
崩解剂
双活性成分
润肤剂与软膏基质
调味剂与着色剂
助流剂与润滑剂
杂质
乳酸-乙交酯(LG)聚合物
防腐剂
溶剂
表面活性剂
赋形剂-培训课程
食品相关
掺假物
氨基酸
碳水化合物
色素
脂肪与油脂
香精与香料
功能性成分
婴幼儿配方食品成分
基质材料
防腐剂
蛋白质与氨基酸
甜味剂
食品-培训课程
FCC分析材料
小分子
杂质
系统适用性
培训课程
即将推出
可提取物和浸出物(E&L)
相关药物物质
其他
测定(Assay)
溶出度(Dissolution)
元素杂质(Elemental Impurities)
熔点(Melting Point)
其他-通则(Others-General Chapters)
性能标准(Performance Standards)
塑料(Plastics)
残留溶剂(Residual Solvents)
系统适用性(System Suitability)
培训课程(Training Courses)
可提取物和浸出物(Extractables and Leachables,E&L)
< " data-original="http://bioauxilium.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理USP标准品"> 艾美捷科技代理USP标准品
艾美捷科技代理Norgen Biotek品牌。
Norgen Biotek由Yousef Haj-Ahmad博士于1998年创立。Norgen是一家获得ISO 9001、ISO 13485和ISO 15189认证的全面集成生物技术公司,为科学界提供全面的研究服务,如下
一代测序、核酸提取。
Norgen Biotek公司的产品范围包括:RNA、DNA、外切体和蛋白质提取的样品采集,保存,提取和检测相关产品。
(1)样本采集和保存:用于采集和保存各种样本(包括血液、血浆、尿液、粪便、唾液)的设备等等。
(2)纯化和分离:使用 Norgen 易于使用的试剂盒分离和纯化高质量的 RNA、DNA、蛋白质、外泌体等。
(3)NGS 文库制备试剂盒:简单快速的工作流程,用于准备您的下一个小型文库RNA-seq、RNA-seq 和宏基因组学。
(4)分子诊断:使用 Norgen 的 PCR 和 RT-PCR Taqman 检测试剂盒针对多种病原体。还提供其他引物和探针。
(5)实验室组件:酶、缓冲液、试剂、无核酸酶水、塑料和过滤设备。
< " data-original="http://bioauxilium.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理Norgen Biotek品牌"> 艾美捷科技代理Norgen Biotek品牌
QED Bioscience致力于为生物医药行业提供各类高品质抗体。
QED Bioscience has been designing and manufacturing antibodies for over 20 years, and throughout our history, our goals have remained unchanged: provide the best antibody products and services on the market and support our clients with the expertise and assistance they should expect from a full-spectrum antibody company like QED.
QED Bioscience develops novel monoclonal and polyclonal antibody products for our academic, biotechnology, diagnostic and pharmaceutical research clients. We develop these antibodies using the client’s small molecule, protein, or peptide targets, or by utilizing the target cDNA. We are a full-service corporation, and offer additional immunochemistry services such as purification and conjugation so that we can provide our clients with an antibody product that will work specifically within their system. We also develop monoclonal antibodies with pharmacological activity for enzyme neutralization and inhibition of receptor-ligand interactions, and anti-idiotypic antibodies.
QED Bioscience的主要产品包括:
Agriculture and Food Science Antibodies
Anti-Immunoglobulin Antibodies
Apoptosis Antibodies
Autophagy Antibodies
BioWarfare Antibodies
Cancer Research Antibodies
Cell Adhesion Molecule Antibodies
Coagulation Factor Antibodies
DNA/RNA/Oxidative Stress Antibodies
Drug Antibodies
Enzymes and Enzyme Inhibitor Antibodies
Epitope Tag Antibodies
Growth Factors/Cytokines/Receptor Antibodies
Heat Shock and Stress Protein Antibodies
Hormones and Serum Protein Antibodies
Infectious Disease Antibodies
Ion Channel Antibodies
Matrix Protein/MMP Antibodies
Neuroscience and Signal Transduction Antibodies
Phospho-specific Antibodies
Protein Transcription Antibodies
Reproductive Biology Antibodies
Secondary Antibodies
<更多详情请联系
艾美捷科技有限公司
全国服务热线:400-6800-868
邮箱:sales@amyjet.com
网站:www.amyjet.com

艾美捷科技代理ZEUS Scientific 品牌。
ZEUS Scientific及其前身公司SurModics In Vitro Technologies于1979年成立,2007年合并了BioFX公司。ZEUS Scientific公司提供的产品种类丰富,涵盖多个科研和临床领域,主要包括:蛋白稳定剂(protein stabilization reagents)、比色底物及化学发光底物(colorimetric and chemiluminescent substrates)、DNA和蛋白芯片(activated slides for DNA and protein microarrays)和重组自身免疫抗原,以及辅助试剂,如二抗、封闭试剂、终止液等。此外,其产品还涉及分子生物学、细胞生物学、菌学、遗传学、生物化学、蛋白质学、细胞疗法、临床应用等多个领域。具体产品包括但不限于抗真菌素、维生素、氨基酸、核苷酸、脂类、糖类、白三烯、前列腺素、药理活性化合物、类固醇素结合物等生物分子,以及球蛋白、封闭肽、人蛋白和抗原、小鼠蛋白和抗原等多种蛋白质和抗原。

艾美捷科技代理Mediomics品牌。
Mediomics提供学术研究实验室、即时检测、制药公司以及医疗和环境研究市场所需的创新检测试剂盒和生物传感器。这些快速简单的检测试剂盒将用于定量许多具有生物学和治疗意义的大分子,包括:DNA、生物标志物、激素、抗体、细胞内信号分子、蛋白质-蛋白质复合物、细菌、真菌和病毒。Mediomics 的平台技术已经适用于检测一系列重要的大分子,包括 cAMP、色氨酸、S-腺苷甲硫氨酸、PDE、生物素、胰岛素、C 肽、白蛋白、C 反应蛋白 (hCRP)、IgG、IgM、大肠杆菌等。Mediomics的平台技术将能够生成全新的生物材料,可用于检测开发和治疗产品的开发。
Mediomics 目前拥有四项核心专有技术:
(1)Bridge-It®,灵敏、快速混合和测量 DNA 结合蛋白检测平台;
(2)PINCER,®快速混合和测量生物传感器、生物测定和生物芯片平台;
(3)创新的专有方法,用于筛选和开发用于研究、诊断和治疗的新型高亲和力捕获试剂;
(4)抗血管生成相关疗法。
" data-original="http://bioauxilium.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理Mediomics品牌"> 艾美捷科技代理Mediomics品牌
艾美捷科技代理BBI Solutions品牌诊断原料。
BBI Solutions的产品范围广泛,包括人的抗原、抗体、血清、血浆和临床化学酶等优质原料,还生产世界知名的ELISA试剂盒、生物传感器的标签、黄金纳米粒子和葡萄糖氧化酶等。BBI Solutions提供一系列专业的服务,包括抗体开发、抗体制造、抗原定制、金共轭化等。其独特的抗体开发、侧向流动试验开发和制造服务组合,能够支持客户从概念到商业化的全过程。BBI Solutions拥有专业的研究团队和完善的生产和质控流程,确保了公司产品的高品质。其提供的技术支持涵盖了产品的应用验证、配对使用抗体的推荐等方面,为客户提供了全方位的技术保障。BBI Solutions公司提供试剂专用酶:辣根过氧化物酶、谷氨酸脱氢酶、碱性磷酸酶、尿素酶、胆固醇酯酶,聚链霉亲和素,人源蛋白,单克隆抗体,金纳米颗粒等。
<<< " data-original="http://bioauxilium.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="艾美捷科技代理BBI Solutions品牌诊断原料"> 艾美捷科技代理BBI Solutions品牌诊断原料

艾美捷科技特约代理Avidity Biosciences公司产品。
Avidity Biosciences公司位于美国加州La Jolla,是一家专门从事抗体寡核苷酸结合物(AOC™)技术开发的生物技术公司,此项技术结合了单抗组织选择性和寡核苷酸疗法的精确性,克服了寡核苷酸给药屏障。
Avidity Biosciences is a privately-held biotech company pioneering Antibody Oligonucleotide Conjugates (AOC™). AOCs combine the tissue selectivity of monoclonal antibodies and the precision of oligonucleotide-based therapeutics to overcome barriers to the delivery of oligonucleotides and target genetic drivers of disease.
Antibody oligonucleotide conjugate (AOC™) technology
Avidity’s antibody oligonucleotide conjugate (AOC™) technology utilizes antibodies to target cells and tissues of interest and facilitate the uptake and internalization of oligonucleotide payloads. By combining the cellular and tissue selectivity of antibodies with the selectivity and efficiency of oligo-based approaches, Avidity has demonstrated modulation of disease-related RNAs in diverse cell types and tissues including muscle, heart, liver, tumors and immune cells.
" data-original="http://bioauxilium.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="Avidity Biosciences"> Avidity Biosciences
艾美捷科技代理Gene Tools品牌
Gene Tools是一家生产和销售Morpholino Anti-sense oligos(反义寡核苷酸)的公司,其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成,为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具,已被广泛用于:阻断靶mRNA 翻译 (下调基因);诱导RNA选择性剪接 (下调或上调基因);阻断 miRNA;阻断病毒 RNA;阻断 non-coding RNA。
▍Morpholino介绍
Morpholino属于第三代反义寡核苷酸,主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用,目前已经广泛用于发育生物学和细胞学实验中,并取得了非常好的实验效果。
Morpholino以吗啉环类似物为基本骨架,这种独特的结构特性使得Morpholino 具有以下几个特点:
● 与其他类型的反义寡核苷酸相比,Morpholino 能更好地抵抗核酸酶的作用;
● Morpholino 与靶序列结合后通过空间位阻效应发挥作用, 不激活RNaseH,不引起目标基因mRNA 的降解 ;
● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译,针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切,得到不 同的转录本,可以方便地用于目标基因结构域的突变研究;
● 与靶序列结合能力强,可以渗入mRNA 的二级结构, 并且特异性好。
配合Morpholino 的使用,Gene Tools公司开发了相应的递送系统,可以安全、高效地将Morpholino 输送至胞内,因此,Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外,Morpholino 可以标上荧光基团、亲和标签以及活性反应基团,以供不同的研究需要。

▍Gene Tools公司产品介绍
● Custom Morpholino:可以根据目标基因序列定制设计并合成Morpholino,用于体外细胞实验或某些直接显微注射的模型(如斑马鱼、非洲爪蟾胚胎)。
● Vivo-Morpholino:适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。通过特殊的末端修饰,提高了其穿透细胞膜进入组织细胞的能力,使得在成年动物(主要是小鼠、大鼠)中进行系统性基因功能研究成为可能。
● Prepared Control Oligos:根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。
| 产品名称 | Short Description | Oligo sequence | SKU |
| Standard Control Oligo | Negative control oligo | CCTCTTACCTCAGTTACAATTTATA | PCO-StandardControl-100 |
| Vivo-Morpholino Standard Control Oligo | Negative Vivo-Morpholino control oligo | CCTCTTACCTCAGTTACAATTTATA | PCO-VivoStandardControl-100 |
| Random Control Oligo 25-N | 25-base random sequence mixture | NNNNNNNNNNNNNNNNNNNNNNNNN | PCO-RandomControl-25N-100 |
| Zebrafish p53 oligo | Danio rerio apoptosis suppression oligo | GCGCCATTGCTTTGCAAGAATTG | PCO-ZebrafishP53-100 |
| Zebrafish Chordin Positive Control Oligo | Danio rerio Chordin positive control oligo | ATCCACAGCAGCCCCTCCATCATCC | PCO-ZebrafishChordin-100-F |
| Clawed Frog Beta Catenin Positive Control Oligo | Xenopus laevis Beta Catenin antisense oligo | TTTCAACCGTTTCCAAAGAACCAGG | PCO-BetaCatenin-100-F |
| Green Fluorescent Protein Positive Control | Translation blocker for GFP target | ACAGCTCCTCGCCCTTGCTCACCAT | PCO-GFPControl-100 |
| Vivo-Morpholino GFP Positive Control | Translation blocker for GFP target (Vivo-Morpholino) | ACAGCTCCTCGCCCTTGCTCACCAT | PCO-VivoGFPControl-100 |
| Fluoresceinated Vivo-Morpholino Std Control | Negative Vivo-Morpholino control oligo with 5'Fluorescein | CCTCTTACCTCAGTTACAATTTATA | PCO-FluorVivoStandardControl-100-F |
● Endo-Porter:为了解决Morpholino在体外培养细胞中摄取效率低的问题,Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。
地址:武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话:18995651644
传真:15172469628
邮箱:sales@amyjet.com
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